How often can you use it: Daily. While caviar-infused creams can be used day and night, Green recommends using masks and exfoliants containing the ingredient more sparingly, ideally only one to two times per week.
In this study, caviar (sturgeon eggs) was used to elucidate its roles in adiponectin production and skin anti-aging. Recently, caviar has been largely used not only as a nutritional food, but also in cosmetic products. In particular, it has been reported that docosahexaenoic acid (DHA), as one of the main phospholipid components of caviar extract, induces intracellular lipid accumulation and the expression of adiponectin in adipocytes. Although adipocytes are well known to be associated with the skin dermis by secreting various factors (e.g., adiponectin), the effects of caviar extract and DHA on the skin are not well studied. Here, we demonstrate the effects of caviar extract and DHA on adipocyte differentiation and adiponectin production, resulting in a preventive role in UV-irradiated skin aging. Caviar extract and DHA enhanced adipocyte differentiation and promoted the synthesis of transcription factors controlling adipocyte differentiation and adiponectin. In addition, the mRNA expression levels of matrix metalloproteinase-1 (MMP-1) were decreased in UVB-irradiated Hs68 fibroblasts that were cultured in conditioned medium from caviar extract or DHA-treated differentiated adipocytes. Taken together, these results indicate that caviar extract and DHA induce adipocyte differentiation and adiponectin production, thereby inhibiting UVB-induced premature skin aging via the suppression of MMP-1 production.
Adipocytes are associated with the dermis by secreting various factors such as adiponectin and leptin that influence other tissues and contribute to skin physiology . Adiponectin is an adipokine secreted from adipocytes that affects energy processes and is involved in lipid metabolism [9,10]. Recent studies reported that adiponectin has beneficial effects on cutaneous wound-healing processes and anti-inflammation properties in skin [11,12,13]. Furthermore, the treatment of exogenous adiponectin suppressed UV-induced skin photoaging through not only inhibiting matrix metalloproteinase-1 (MMP-1) expression but also increasing type I procollagen synthesis in human dermal fibroblasts (HDFs) . The features of aged skin such as wrinkles and sagging are mainly due to the loss of collagen and the integrity of elastic fiber in dermal skin [14,15]. UV irradiation induces the expression of MMP, which is responsible for the degradation of the extracellular matrix (ECM) by cleaving collagen fibers, and reduces the production of collagens, thereby resulting in the loss of resiliency and tensile strength . Here, we aimed to determine the anti-photoaging effects of caviar extract and docosahexaenoic acid (DHA) in dermal fibroblasts by increasing the production of adiponectin.
Caviar is composed of sturgeon (Acipenseridae family) eggs, and is known as a high-quality food containing a variety of fatty acids, amino acids, and minerals. In particular, a number of studies analyzing caviar lipid composition have been reported since the lipids derived from fish eggs were proposed as important nutrients for human health, and the lipid classes serve different biological functions in organisms. Among them, caviar contains high levels of fatty acids, including polyunsaturated fatty acids (PUFAs), DHA, and eicosapentaenoic acid (EPA), and these fatty acids have been shown to be beneficial for skin health [17,18,19]. Although some cosmetic products using caviar have emerged on the market with the function of skin anti-aging, the effects of caviar in the skin remain unclear yet.
Caviar extract increased adipocyte differentiation. (A) 3T3-L1 cells were treated with caviar extract at the indicated concentrations for 2 days. Cell viability was examined by the MTT assay. The means SDs are the average of three independent experiments. (B) The differentiated 3T3-L1 adipocytes were induced with or without treatment of caviar extract for 6 days. Observation of morphology and Oil Red O staining of 3T3-L1 cells were photographed using a light microscope (Χ 200). Lipid droplets are stained red, and the data are representative of three independent experiments. (C) PPARγ, SREBP-1a, and C/EBPα mRNAs were measured by RT-qPCR. The means SEs are the average of three independent experiments. * p < 0.05, ** p < 0.01, and *** p < 0.001 indicate a significant difference from the control.
DHA increased adipocyte differentiation. The 3T3-L1 cells were differentiated with treatment of DHA, caviar extract, or troglitazone for 6 days. (A) Observation of morphology and Oil Red O staining of differentiated 3T3-L1 cells were photographed using a light microscope (Χ200). Lipid droplets are stained red, and the data are representative of three independent experiments. PPARγ, SREBP-1a, and C/EBPα (B) mRNA and (C) protein levels were measured by RT-qPCR and immunoblotting. The means SEs are the average of three independent experiments. * p < 0.05, ** p < 0.01, and *** p < 0.001 indicate a significant difference from the control.
In this study, we first evaluated whether caviar extract contributes to an increase in adipocyte differentiation. The results showed that the caviar extract enhanced adipocyte differentiation by an increase in both intracellular lipid accumulation and gene expression levels of adipogenesis-related transcription factors (Figure 1). Several transcription factors are involved in the process of adipocyte differentiation and adiponectin production, such as PPARγ, C/EBPα, and SREBP-1a, suggesting that caviar extract engages the regulation of transcriptional factors to enhance adipocyte differentiation [36,37]. As a result, caviar extract increased the mRNA expression levels of PPARγ and SREBP-1a, but not C/EBPα. To support our observation, we next quantified the mRNA and protein expression levels of adiponectin with the treatment of caviar extract. We noted that the treatment of caviar extract significantly increased adiponectin expression levels in differentiated adipocytes in a dose-dependent manner compared to the non-treated control (Figure 2A,C). Next, to better define the relation of adiponectin production by the treatment of caviar extract and the effects of it on skin aging, the conditioned medium cultured with caviar extract during the adipocyte differentiation was treated in UVB-induced Hs68 fibroblasts. Indeed, doing so clearly decreased the mRNA expression levels of MMP-1, indicating that the secreted adiponectin in conditioned medium from caviar-extract-treated differentiated adipocytes had an effect on preventing UVB-induced dermal skin aging (e.g., wrinkles or sagging) caused by the degradation of ECM.
Here, we analyzed the lipid composition of caviar extract to identify such phospholipid signatures that may help in understanding the mechanisms of the skin anti-aging effects of caviar extract. As shown in Table 1, oleic acid, palmitic acid, and DHA were the main phospholipids in caviar extract. Based on the previous evidence, we hypothesized that the DHA in caviar extract may be the main component inducing adipocyte differentiation and adiponectin synthesis, thereby preventing the UVB-induced MMP-1 expression.
This face mask contains the precious caviar extract to prevent wrinkles and fine lines, combined both hydrolyzed hibiscus esculentus extract and deep sea water to lock-in hydration . Provide your skin a firmer and delicate looks.
Nothing is more pampering than caviar, and the same is true for your skin. This delightful Dead sea cosmetics item by Health & Beauty cosmetics combines the benefits of Dead sea minerals, Hyaluronic acid, and caviar, to create a truly wonderful product for your spa days.
Creanatural Caviar Sevruga Extract brings elegance to cosmetic products. It is a unique extract for sophisticated skin care products. Rich in omega-3 fatty acids and vitamins D, B2 and B12, Creanatural Caviar Sevruga Extract works as natural antioxidant with anti-inflammatory effects.
Precious Elixir Pearl & Caviar has been specially formulated to revitalize and hydrate your skin. The high volume of protein and vitamins from the pearl and caviar extracts promote cell renovation, which decreases the appearance of wrinkles, and provides nutrients for cell maintenance and regeneration.
There are plenty of high-end skincare lines that promote having caviar in their ingredients, but not everyone can afford to dish out several hundred dollars on a jar of face cream. However, with the growing scientific research on caviar extract in skincare and the massive wave of demand for youth-boosting skin products, low and behold are brands or spa services now offering the coveted caviar extract!
At Botanica Day Spa in Clearwater, FL, anyone can receive the luxurious caviar facial. At our spa, this facial service uses pure caviar extract, pearl extract, and a blend of Phyto extracts for a paradise of divine skincare ingredients to bathe your skin. What is Phyto extracts though They are plant-derived extracts indigenous to South Asia and Africa that are akin to a natural, topical alternative to Botox! These extracts pack a wild punch against wrinkles and if used regularly, can smooth skin and redefine signs of aging like magic.
Caviar has a cell format similar to human skin and is known to provide unparalleled nourishment and mineralization of the skin. The caviar extract used in Caviar of Switzerland products comes from a special sturgeon farm in France and is then sent to a Swiss laboratory to be formulated for cosmetic use. This is the finest caviar used in aesthetics. It is certified by the Swiss government and approved by the FDA and the U.S. Wild Life and Fish Department helping to protect endangered species. 59ce067264